Role of Pore-Forming Toxins in Bacterial Infectious Diseases

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Role of pore-forming toxins in bacterial infectious diseases.

Pore-forming toxins (PFTs) are the most common bacterial cytotoxic proteins and are required for virulence in a large number of important pathogens, including Streptococcus pneumoniae, group A and B streptococci, Staphylococcus aureus, Escherichia coli, and Mycobacterium tuberculosis. PFTs generally disrupt host cell membranes, but they can have additional effects independent of pore formation....

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ژورنال

عنوان ژورنال: Microbiology and Molecular Biology Reviews

سال: 2013

ISSN: 1092-2172,1098-5557

DOI: 10.1128/mmbr.00052-12